Actor Johnny Depp may be a chameleon on screen, but watch him during any interview, and you'll see only a man whose facial expressions, droopy posture, and mumbled words give away what was once a big secret: Depp suffers from severe anxiety. Indeed, the actor's anxiety has been a major source of depression and unease, so much so that Depp has access to therapists at all times, even on film sets, who help advise him on how best to deal with his anxiety and keep it from dragging him into severe depression.